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                  <mods:namePart>Riquelme, Sebastián</mods:namePart>
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                  <mods:namePart>Saéz, Vania</mods:namePart>
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                  <mods:namePart>Escobar Avello, Danilo</mods:namePart>
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                  <mods:namePart>Vergara, C.</mods:namePart>
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                  <mods:namePart>Fuentealba, Cecilia</mods:namePart>
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                  <mods:namePart>Bustamante, Luis</mods:namePart>
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                  <mods:namePart>von Baer, D.</mods:namePart>
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               <mods:name>
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                  <mods:namePart>Jara, Paola</mods:namePart>
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               <mods:name>
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                  <mods:namePart>Lamperti, Liliana</mods:namePart>
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                  <mods:namePart>Mardones, Claudia</mods:namePart>
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                  <mods:dateIssued encoding="iso8601">2021-09-02T06:17:56Z2021-09-02T06:17:56Z2019-062021-09-02T06:17:56Z</mods:dateIssued>
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               <mods:abstract>Dietary supplements have become the key to complement deficiencies in the occidental diet and therefore to reduce the incidence of oxidative stress related diseases. A bench-scale extraction procedure was studied to obtain a valuable product rich in phenolic compounds and antioxidant capacity from Pinot Noir grape cane enhanced by storage. Extraction solvent, cane-size, solid:liquid ratio, temperature, and extraction time, were systematically evaluated in order to obtain a natural functional product. Complete chemical characterization of a Pinot Noir grape cane extract produced under bench scale process is presented for the first time. Phenolic profiles of the extracts were characterized by HPLC-PDA-MS/MS and minerals by ICP-OES. Proteins, carbohydrates and lignins were also evaluated. The main phenolic compounds in the final product were stilbenoids, flavan-3-ols, procyanidins, and flavonols, with 6.53%, 4.84%, 2.11%, and 0.25%, respectively on a dry matter basis. Other chemical constituents were carbohydrates (27%), minerals (1%) and lignins (38.7%). The antioxidant capacity of the product was demonstrated using chemical assays (TEACABTS/CUPRAC and ORAC-FL) and endothelial cells model. The extract produced under the described bench scale process using grape cane enhanced by storage have a chemical composition and protecting capacities to be used in functional foods industry.</mods:abstract>
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               <mods:accessCondition type="useAndReproduction">cc-by-nc (c) Sociedad Chilena de Química, 2019 https://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess</mods:accessCondition>
               <mods:subject>
                  <mods:topic>Raïms</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Antioxidants</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Fenols</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Grapes</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Antioxidants</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Phenols</mods:topic>
               </mods:subject>
               <mods:titleInfo>
                  <mods:title>Bench-scale extraction of stilbenoids and other phenolics from stored grape canes (Vitis vinifera): Optimization process, chemical characterization, and potential protection against oxidative damage</mods:title>
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