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Modified siRNAs for the study of the PAZ domain Somoza, Álvaro Terrazas Martínez, Montserrat Eritja i Casadellà, Ramon RNA Fixació de proteïnes Modificació química de les proteïnes RNA Protein binding Chemical modification of proteins Chemical modifications aimed at stabilizing the interaction between the 3'-end of siRNAs and the PAZ domain of RISC have been tested for their effect on RNAi activity. Such modifications contribute positively to the stability of siRNAs in human serum. 2021-08-31T11:41:03Z 2021-08-31T11:41:03Z 2010-05-19 2021-08-31T11:41:03Z info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Versió postprint del document publicat a: https://doi.org/10.1039/C003221B Chemical Communications, 2010, vol. 46, p. 4270-4272 https://doi.org/10.1039/C003221B (c) Somoza, Álvaro et al., 2010 info:eu-repo/semantics/openAccess Royal Society of Chemistry Articles publicats en revistes (Química Inorgànica i Orgànica)