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oai:recercat.cat:2445/1764162025-12-06T04:06:46Zcom_2072_1057col_2072_478798col_2072_478858col_2072_478916col_2072_478917

Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk Estruch Riba, Ramon Pintó Sala, Xavier Vidal i Cortada, Josep Ros Rahola, Emilio Casas Rodríguez, Rosa M. Galera Cusí, Ana PREDIMED Study Investigators Àcids grassos Malalties cardiovasculars Obesitat Cuina mediterrània Fatty acids Cardiovascular diseases Obesity Mediterranean cooking Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia. 2021-04-19T08:59:15Z 2021-04-19T08:59:15Z 2019-06-29 2021-04-19T08:59:15Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.3390/nu11071493 Nutrients, 2019, vol. 11, num. 7 https://doi.org/10.3390/nu11071493 info:eu-repo/grantAgreement/EC/FP7/340918/EU//PREDIMED PLUS cc-by (c) Estruch Riba, Ramon et al., 2019 http://creativecommons.org/licenses/by/3.0/es info:eu-repo/semantics/openAccess MDPI Articles publicats en revistes (Ciències Clíniques)