2026-04-17T03:19:25Zhttps://recercat.cat/oai/requestoai:recercat.cat:2445/1757992025-12-05T12:08:32Zcom_2072_1057col_2072_478916col_2072_478917
RECERCAT
author
Dalmau Llorca, Maria Rosa
author
Aguilar Martín, Carina
author
Carrasco Querol, Noèlia
author
Hernández Rojas, Zojaina
author
Forcadell Drago, Emma
author
Rodríguez Cumplido, Dolores
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Pepió i Vilaubí, Josep M.
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Castro Blanco, Elisabet
author
Gonçalves, Alessandra Queiroga
author
Fernández Sáez, José
2021-03-26T09:55:01Z2021-03-26T09:55:01Z2021-02-242021-03-25T13:17:59Z
Background: Oral anticoagulants (OAs) are the treatment to prevent stroke in atrial fibrillation (AF). Anticoagulant treatment choice in non-valvular atrial fibrillation (NVAF) must be individualized, taking current guidelines into account. Adequacy of anticoagulant therapy under the current criteria for NVAF in real-world primary care is presented. Methods: Cross-sectional study, with real-world data from patients treated in primary care (PC). Data were obtained from the System for the Improvement of Research in Primary Care (SIDIAP) database, covering 60,978 NVAF-anticoagulated patients from 287 PC centers in 2018. Results: In total, 41,430 (68%) were treated with vitamin K antagonists (VKAs) and 19,548 (32%) NVAF with direct-acting oral anticoagulants (DOACs). Inadequate prescription was estimated to be 36.0% and 67.6%, respectively. Most DOAC inadequacy (77.3%) was due to it being prescribed as a first-line anticoagulant when there was no history of thromboembolic events or intracranial hemorrhage (ICH). A total of 22.1% had missing estimated glomerular filtration rate (eGFR) values. Common causes of inadequate VKA prescription were poor control of time in therapeutic range (TTR) (98.8%) and ICH (2.2%). Conclusions: Poor adequacy to current criteria was observed, being inadequacy higher in DOACs than in VKAs. TTR and GFR should be routinely calculated in electronic health records (EHR) to facilitate decision-making and patient safety.
cc by (c) Dalmau Llorca et al., 2021 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess
Fibril·lació auricular
Anticoagulants (Medicina)
Atrial fibrillation
Anticoagulants (Medicine)
Oral Anticoagulant Adequacy in Non-Valvular Atrial Fibrillation in Primary Care: A Cross-Sectional Study Using Real-World Data (Fantas-TIC Study)
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion