2026-04-17T17:05:55Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1757992025-12-05T12:08:32Zcom_2072_1057col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Dalmau Llorca, Maria Rosa author Aguilar Martín, Carina author Carrasco Querol, Noèlia author Hernández Rojas, Zojaina author Forcadell Drago, Emma author Rodríguez Cumplido, Dolores author Pepió i Vilaubí, Josep M. author Castro Blanco, Elisabet author Gonçalves, Alessandra Queiroga author Fernández Sáez, José author 2021-03-26T09:55:01Z 2021-03-26T09:55:01Z 2021-02-24 2021-03-25T13:17:59Z Background: Oral anticoagulants (OAs) are the treatment to prevent stroke in atrial fibrillation (AF). Anticoagulant treatment choice in non-valvular atrial fibrillation (NVAF) must be individualized, taking current guidelines into account. Adequacy of anticoagulant therapy under the current criteria for NVAF in real-world primary care is presented. Methods: Cross-sectional study, with real-world data from patients treated in primary care (PC). Data were obtained from the System for the Improvement of Research in Primary Care (SIDIAP) database, covering 60,978 NVAF-anticoagulated patients from 287 PC centers in 2018. Results: In total, 41,430 (68%) were treated with vitamin K antagonists (VKAs) and 19,548 (32%) NVAF with direct-acting oral anticoagulants (DOACs). Inadequate prescription was estimated to be 36.0% and 67.6%, respectively. Most DOAC inadequacy (77.3%) was due to it being prescribed as a first-line anticoagulant when there was no history of thromboembolic events or intracranial hemorrhage (ICH). A total of 22.1% had missing estimated glomerular filtration rate (eGFR) values. Common causes of inadequate VKA prescription were poor control of time in therapeutic range (TTR) (98.8%) and ICH (2.2%). Conclusions: Poor adequacy to current criteria was observed, being inadequacy higher in DOACs than in VKAs. TTR and GFR should be routinely calculated in electronic health records (EHR) to facilitate decision-making and patient safety. Fibril·lació auricular Anticoagulants (Medicina) Atrial fibrillation Anticoagulants (Medicine) Oral Anticoagulant Adequacy in Non-Valvular Atrial Fibrillation in Primary Care: A Cross-Sectional Study Using Real-World Data (Fantas-TIC Study)