2026-04-18T06:18:16Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1746742025-12-04T19:24:36Zcom_2072_1057col_2072_478858col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Cuesta, Martín author Fuentes, Manuel author Rubio, Miguel author Bordiú, Elena author Barabash, Ana author García de la Torre, Nuria author Rojo Martínez, Gemma author Valdes, Sergio author Soriguer, Federico author Vendrell, Joan Josep author Urrutia Etxebarria, Inés María author Ortega Martínez de Victoria, Emilio author Montanya Mias, Eduard author Menendez, Eldelmiro author Lago Sampedro, Ana author Gomis, Ramon, 1946- author Goday Arnó, Albert author Castell, Conxa author Badia Guillén, Rocío author Girbés, Juan author Gaztambide, Sonia author Franch Nadal, Josep author Delgado Álvarez, Elías author Chaves, Felipe Javier author Castano, Luis author Calle Pascual, Alfonso L. author 2021-03-05T07:46:49Z 2021-03-05T07:46:49Z 2020 Introduction: Metabolic syndrome (MetS) is an important predictor of cardiovascular mortality. Identification of occurrence and regression trends of MetS could permit elaboration of preventive strategies with new targets. The objective of this study was to analyze the occurrence and regression rates of MetS and its associated factors in the representative cohort of Spain of the di@bet.es study. Research design and methods: The di@bet.es study is a prospective cohort where 5072 people representative of the Spanish population over 18 years of age were randomly selected between 2009 and 2010. Follow-up was a median of 7.5 (IQR 7.2-7.9) years, with 2408 (47%) participating subjects. A total of 1881 (78%) subjects had all the pertinent data available and were included in this study. Results: Of the 1146 subjects without baseline criteria for MetS, 294 (25.7%) developed MetS during follow-up, while of the 735 patients with prior MetS, 148 (20.1%) presented regression. Adjusted MetS incidence per 1000 person-years was 38 (95% CI 32 to 44), while regression incidence was 36 (95% CI 31 to 41). Regression rate was independently higher than incidence rate in the following: women, subjects aged 18-45, university-degree holders, patients without central obesity, without hypertension, as well as those with body mass index of <25 kg/m(2). Lower progression and higher regression rates were observed with an adapted 14-point Mediterranean Diet adherence screener questionnaire score of >11 in both groups and with >500 and >2000 MET-min/week of physical activity, respectively. Conclusions: This study provides MetS incidence and regression rates, and identifies the target population for intervention strategies in Spain and possibly in other countries. Estils de vida Epidemiologia Síndrome metabòlica Lifestyles Epidemiology Metabolic syndrome Incidence and regression of metabolic syndrome in a representative sample of the Spanish population: results of the cohort di@bet.es study