2026-04-13T03:14:38Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1742842025-12-05T12:34:32Zcom_2072_1057col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Deschasaux, Mélanie author Huybrechts, Inge author Julia, Chantal author Hercberg, Serge author Egnell, Manon author Srour, Bernard author Kesse-Guyot, Emmanuelle author Latino-Martel, Paule author Biessy, Carine author Casagrande, Corinne author Murphy, Neil author Jenab, Mazda author Ward, Heather A. author Weiderpass, Elisabete author Overvad, Kim author Tjønneland, Anne author Rostgaard-Hansen, Agnetha Linn author Boutron-Ruault, Marie-Christine author Mancini, Francesca Romana author Mahamat-Saleh, Yahya author Kühn, Tilman author Katzke, Verena author Bergmann, Manuela M. author Schulze, Matthias B. author Trichopoulou, Antonia author Karakatsani, Anna author Peppa, Eleni author Masala, Giovanna author Agnoli, Claudia author Santucci de Magistris, Maria author Tumino, Rosario author Sacerdote, Carlotta author Boer, Jolanda M. A. author Verschuren, W. M. Monique author van der Schouw, Yvonne T. author Skeie, Guri author Braaten, Tonje author Redondo, M. Luisa author Agudo, Antonio author Petrova, Dafina author Colorado-Yohar, Sandra author Barricarte, Aurelio author Amiano, Pilar author Sonestedt, Emily author Ericson, Ulrika author Otten, Julia author Sundström, Björn author Wareham, Nicholas J. author Forouhi, Nita G author Vineis, Paolo author Tsilidis, Konstantinos K. author Knuppel, Anika author Papier, Keren author Ferrari, Pietro author Riboli, Elio author Gunter, Marc J. author Touvier, Mathilde author 2021-02-24T19:08:50Z 2021-02-24T19:08:50Z 2020-09-16 2021-02-16T08:45:49Z Objective: To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which grades the nutritional quality of food products and is used to derive the Nutri-Score front-of-packet label to guide consumers towards healthier food choices, is associated with mortality. Design: Population based cohort study. Setting: European Prospective Investigation into Cancer and Nutrition (EPIC) cohort from 23 centres in 10 European countries. Participants: 521 324 adults; at recruitment, country specific and validated dietary questionnaires were used to assess their usual dietary intakes. A FSAm-NPS score was calculated for each food item per 100 g content of energy, sugars, saturated fatty acids, sodium, fibre, and protein, and of fruit, vegetables, legumes, and nuts. The FSAm-NPS dietary index was calculated for each participant as an energy weighted mean of the FSAm-NPS score of all foods consumed. The higher the score the lower the overall nutritional quality of the diet. Main outcome measure: Associations between the FSAm-NPS dietary index score and mortality, assessed using multivariable adjusted Cox proportional hazards regression models. Results: After exclusions, 501 594 adults (median follow-up 17.2 years, 8 162 730 person years) were included in the analyses. Those with a higher FSAm-NPS dietary index score (highest versus lowest fifth) showed an increased risk of all cause mortality (n=53 112 events from non-external causes; hazard ratio 1.07, 95% confidence interval 1.03 to 1.10, P<0.001 for trend) and mortality from cancer (1.08, 1.03 to 1.13, P<0.001 for trend) and diseases of the circulatory (1.04, 0.98 to 1.11, P=0.06 for trend), respiratory (1.39, 1.22 to 1.59, P<0.001), and digestive (1.22, 1.02 to 1.45, P=0.03 for trend) systems. The age standardised absolute rates for all cause mortality per 10 000 persons over 10 years were 760 (men=1237; women=563) for those in the highest fifth of the FSAm-NPS dietary index score and 661 (men=1008; women=518) for those in the lowest fifth. Conclusions: In this large multinational European cohort, consuming foods with a higher FSAm-NPS score (lower nutritional quality) was associated with a higher mortality for all causes and for cancer and diseases of the circulatory, respiratory, and digestive systems, supporting the relevance of FSAm-NPS to characterise healthier food choices in the context of public health policies (eg, the Nutri-Score) for European populations. This is important considering ongoing discussions about the potential implementation of a unique nutrition labelling system at the European Union level. Nutrició Mortalitat Nutrition Mortality Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries