2026-04-19T11:35:13Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1734232025-12-05T12:37:26Zcom_2072_1057col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Christakoudi, Sofia author Tsilidis, Konstantinos K. author Muller, David C. author Freisling, Heinz author Weiderpass, Elisabete author Overvad, Kim author Soderberg, Stefan author Haggstrom, Christel author Pischon, Tobias author Dahm, Christina C. author Zhang, Jie author Tjønneland, Anne author Halkjær, Jytte author MacDonald, Conor author Boutron-Ruault, Marie-Christine author Mancini, Francesca Romana author Kühn, Tilman author Kaaks, Rudolf author Schulze, Matthias B. author Trichopoulou, Antonia author Karakatsani, Anna author Peppa, Eleni author Masala, Giovanna author Pala, Valeria author Panico, Salvatore author Tumino, Rosario author Sacerdote, Carlotta author Quirós, José Ramón author Agudo, Antonio author Sánchez, María José author Cirera, Lluís author Barricarte, Aurelio author Amiano, Pilar author Memarian, Ensieh author Sonestedt, Emily author Bueno de Mesquita, H. Bas author May, Anne M. author Khaw, Kay‑Tee author Wareham, Nicholas J. author Tong, Tammy Y. N. author Huybrechts, Inge author Noh, Hwayoung author Aglago, Elom K. author Ellingjord-Dale, Merete author Ward, Heather A. author Aune, Dagfinn author Riboli, Elio author 2021-01-25T13:18:34Z 2021-01-25T13:18:34Z 2020-09-03 2021-01-25T08:05:47Z Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI<18.5 kg/m(2)) or obese (BMI<greater than or equal to>30 kg/m(2)) categories, while the highest quartile of ABSI separated 18-39% of the individuals within each BMI category, which had 22-55% higher risk of death. In conclusion, only a waist index independent of BMI by design, such as ABSI, complements BMI and enables efficient risk stratification, which could facilitate personalisation of screening, treatment and monitoring. Obesitat Mortalitat Factors de risc en les malalties Obesity Mortality Risk factors in diseases A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort