2026-04-17T17:08:57Zhttps://recercat.cat/oai/requestoai:recercat.cat:2445/1713692025-12-05T14:25:23Zcom_2072_1057col_2072_478777col_2072_478816col_2072_478917
RECERCAT
author
Castro-Torres, Rubén Darío
author
Busquets Figueras, Oriol
author
Parcerisas, Antoni
author
Verdaguer Cardona, Ester
author
Olloquequi, Jordi
author
Ettcheto Arriola, Miren
author
Beas Zárate, Carlos
author
Folch, Jaume
author
Camins Espuny, Antoni
author
Auladell i Costa, M. Carme
2020-10-19T18:32:00Z2020-10-19T18:32:00Z2020-08-132020-10-19T18:32:01Z
The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control of a wide array of functions within the cell. In the central nervous system (CNS), JNKs are involved in neuronal polarization, starting from the cell division of neural stem cells and ending with their final positioning when migrating and maturing. This review will focus mostly on isoform JNK1, the foremost contributor of total JNK activity in the CNS. Throughout the text, research from multiple groups will be summarized and discussed in order to describe the involvement of the JNKs in the different steps of neuronal polarization. The data presented support the idea that isoform JNK1 is highly relevant to the regulation of many of the processes that occur in neuronal development in the CNS.
cc-by (c) Castro-Torres, Rubén Darío. et al., 2020 http://creativecommons.org/licenses/by/3.0/es info:eu-repo/semantics/openAccess
Proteïnes quinases
Evolució del cervell
Protein kinases
Evolution of the brain
Involvement of JNK1 in neuronal polarization during brain development
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion