<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-04-18T06:15:43Z</responseDate><request verb="GetRecord" identifier="oai:www.recercat.cat:2445/164999" metadataPrefix="mets">https://recercat.cat/oai/request</request><GetRecord><record><header><identifier>oai:recercat.cat:2445/164999</identifier><datestamp>2025-12-05T04:24:18Z</datestamp><setSpec>com_2072_1057</setSpec><setSpec>col_2072_478809</setSpec><setSpec>col_2072_478917</setSpec></header><metadata><mets xmlns="http://www.loc.gov/METS/" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" ID="&#xa;&#x9;&#x9;&#x9;&#x9;DSpace_ITEM_2445-164999" TYPE="DSpace ITEM" PROFILE="DSpace METS SIP Profile 1.0" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd" OBJID="&#xa;&#x9;&#x9;&#x9;&#x9;hdl:2445/164999">
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                  <mods:namePart>Darbà, Josep</mods:namePart>
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                  <mods:namePart>Ascanio, Meritxell</mods:namePart>
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               <mods:name>
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                  <mods:namePart>Carvalho, Davide</mods:namePart>
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               <mods:name>
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                  <mods:namePart>Conde, Vasco</mods:namePart>
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                  <mods:namePart>Pedersen, Kasper S.</mods:namePart>
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                  <mods:dateIssued encoding="iso8601">2020-06-10T08:05:43Z2020-12-20T06:10:18Z2019-12-202020-06-10T08:05:43Z</mods:dateIssued>
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               <mods:abstract>Objectives: To assess the cost-effectiveness of insulin degludec (degludec) versus insulin glargine (glargine) U100 from a Portuguese healthcare perspective using data from SWITCH 1 &amp; 2 trials. - - - Methods: A short-term model estimated cost-effectiveness of degludec versus glargine U100 in type 1 diabetes (T1DM) basal bolus (B/B) and type 2 diabetes (T2DM) basal oral therapy (BOT) patients. The model captured hypoglycaemia rates and insulin dosing. Clinical outcomes were obtained from SWITCH 1 &amp; 2. Disutilities related to hypoglycaemic events and insulin, needles and blood glucose tests costs were also included. Benefits were measured in QALYs. One-way and probabilistic sensitivity analyses were conducted (...)</mods:abstract>
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               <mods:accessCondition type="useAndReproduction">cc-by-nc-nd (c) Cortex - Publicacoes Tecnicas e Cientificas, 2019 http://creativecommons.org/licenses/by-nc-nd/3.0/es info:eu-repo/semantics/openAccess</mods:accessCondition>
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                  <mods:topic>Anàlisi cost-benefici</mods:topic>
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                  <mods:topic>Salut pública</mods:topic>
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               <mods:subject>
                  <mods:topic>Diabetis</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Insulina</mods:topic>
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               <mods:subject>
                  <mods:topic>Portugal</mods:topic>
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               <mods:subject>
                  <mods:topic>Cost effectiveness</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Public health</mods:topic>
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               <mods:subject>
                  <mods:topic>Diabetes</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Insulin</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Portugal</mods:topic>
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               <mods:titleInfo>
                  <mods:title>Cost-effectiveness of insulin degludec versus insulin glargine U100 in patients with type 1 and type 2 diabetes in Portugal: evidence from SWITCH 1&amp;2 trials</mods:title>
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