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               <dc:title>Cost-effectiveness of insulin degludec versus insulin glargine U100 in patients with type 1 and type 2 diabetes in Portugal: evidence from SWITCH 1&amp;2 trials</dc:title>
               <dc:creator>Darbà, Josep</dc:creator>
               <dc:creator>Ascanio, Meritxell</dc:creator>
               <dc:creator>Carvalho, Davide</dc:creator>
               <dc:creator>Conde, Vasco</dc:creator>
               <dc:creator>Pedersen, Kasper S.</dc:creator>
               <dc:subject>Anàlisi cost-benefici</dc:subject>
               <dc:subject>Salut pública</dc:subject>
               <dc:subject>Diabetis</dc:subject>
               <dc:subject>Insulina</dc:subject>
               <dc:subject>Portugal</dc:subject>
               <dc:subject>Cost effectiveness</dc:subject>
               <dc:subject>Public health</dc:subject>
               <dc:subject>Diabetes</dc:subject>
               <dc:subject>Insulin</dc:subject>
               <dc:subject>Portugal</dc:subject>
               <dc:description>Objectives: To assess the cost-effectiveness of insulin degludec (degludec) versus insulin glargine (glargine) U100 from a Portuguese healthcare perspective using data from SWITCH 1 &amp; 2 trials. - - - Methods: A short-term model estimated cost-effectiveness of degludec versus glargine U100 in type 1 diabetes (T1DM) basal bolus (B/B) and type 2 diabetes (T2DM) basal oral therapy (BOT) patients. The model captured hypoglycaemia rates and insulin dosing. Clinical outcomes were obtained from SWITCH 1 &amp; 2. Disutilities related to hypoglycaemic events and insulin, needles and blood glucose tests costs were also included. Benefits were measured in QALYs. One-way and probabilistic sensitivity analyses were conducted (...)</dc:description>
               <dc:date>2020-06-10T08:05:43Z</dc:date>
               <dc:date>2020-12-20T06:10:18Z</dc:date>
               <dc:date>2019-12-20</dc:date>
               <dc:date>2020-06-10T08:05:43Z</dc:date>
               <dc:type>info:eu-repo/semantics/article</dc:type>
               <dc:type>info:eu-repo/semantics/acceptedVersion</dc:type>
               <dc:relation>Versió postprint del document publicat a: http://www.revportdiabetes.com/rpd-dez-2019/</dc:relation>
               <dc:relation>Revista Portuguesa de Diabetes, 2019, vol. 14, num. 4, p. 141-150</dc:relation>
               <dc:rights>cc-by-nc-nd (c) Cortex - Publicacoes Tecnicas e Cientificas, 2019</dc:rights>
               <dc:rights>http://creativecommons.org/licenses/by-nc-nd/3.0/es</dc:rights>
               <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
               <dc:publisher>Cortex - Publicacoes Tecnicas e Cientificas</dc:publisher>
               <dc:source>Articles publicats en revistes (Economia)</dc:source>
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