2026-04-17T03:04:07Zhttps://recercat.cat/oai/request
oai:recercat.cat:2445/1629622025-12-05T14:52:02Zcom_2072_1057col_2072_478917col_2072_478924
RECERCAT author Latorre Moratalla, Mariluz author Comas Basté, Oriol author Bover i Cid, Sara author Vidal Carou, Ma. Carmen 2020-05-29T06:44:30Z2020-05-29T06:44:30Z2017-012020-05-29T06:44:30Z Tyramine and histamine are the main dietary bioactive amines related to acute adverse health effects. Dry fermented sausages can easily accumulate high levels of these hazards and are frequently consumed in Spain. The present work aims to assess the exposure to tyramine and histamine from the consumption of dry fermented sausages by the Spanish population and to assess the risk to suffer acute health effects from this exposure. A probabilistic estimation of the exposure to these hazards was derived combining probability distributions of these amines in dry fermented sausages (n = 474) and their consumption by the Spanish population. The mean dietary exposure to tyramine and histamine was 6.2 and 1.39 mg/meal, respectively. The risk of suffering hypertensive crisis or histamine intoxication by healthy population due to tyramine or histamine intake, respectively, exclusively from dry fermented sausages, can be considered negligible. For individuals under treatment with MAOI drugs, the probability to surpass the safe threshold dose (6 mg/meal) was estimated as 34%. For patients with histamine intolerance, even the presence of this amine in food is not tolerable and it could be estimated that 7000 individuals per million could be at risk to suffer the related symptoms after consuming dry fermented sausages cc-by-nc-nd (c) Elsevier Ltd, 2017 http://creativecommons.org/licenses/by-nc-nd/3.0/es info:eu-repo/semantics/openAccess Epidemiologia Nutrició Aliments fermentats Histamina Tolerància Embotits Espanya Epidemiology Nutrition Fermented foods Histamine Toleration Sausages Spain Tyramine and histamine risk assessment related to consumption of dry fermented sausages by the Spanish population info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion