2026-04-17T01:13:35Zhttps://recercat.cat/oai/request
oai:recercat.cat:2445/1597312025-11-20T14:36:25Zcom_2072_1057col_2072_478913col_2072_478917col_2072_478924
RECERCAT author Bernardi, Stefano author Bo', Cristian Del author Guglielmetti, Simone author Cherubini, Antonio author Kroon, Paul A. author Kirkup, Benjamin author Hidalgo Liberona, Nicole author Peron, Gregorio author González-Domínguez, Raúl author Andrés Lacueva, Ma. Cristina author Riso, Patrizia 2020-05-12T15:23:27Z2020-05-12T15:23:27Z2019-08-162020-05-12T15:23:27Z The inevitable rise of the proportion of people aged >65 years worldwide is paralleled by an increased burden of chronic diseases often associated with low-grade systemic inflammation. Recent findings suggest a link between inflammation and intestinal permeability (IP), a condition characterized by an impairment of intestinal barrier function which enables the translocation of dietary and bacterial factors into the blood activating the host immune system [1,2]. Dietary components can be significant modulators of inflammation and IP, and can also affect the intestinal microbial ecosystem. In the context of a diet-microbiota-IP axis in older subjects, dietary bioactives such as polyphenols may play a significant protective role due to their widely reported antioxidant and immunomodulatory properties and potential to regulate IP [3-6]. cc-by (c) Bernard, Stefano et al., 2019 http://creativecommons.org/licenses/by/3.0/es info:eu-repo/semantics/openAccess Malalties cròniques Persones grans Malalties inflamatòries intestinals Chronic diseases Older people Inflammatory bowel diseases Role of a Polyphenol-Rich Dietary Pattern in the Modulation of Intestinal Permeability in Older Subjects: The MaPLE Study info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion