2026-04-17T12:29:46Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1576412025-12-05T14:10:07Zcom_2072_1057col_2072_478815col_2072_478917

00925njm 22002777a 4500 dc Fornaguera, Cristina author García Celma, Ma José author 2020-04-27T10:08:39Z 2020-04-27T10:08:39Z 2017-10-12 2020-04-27T10:08:39Z Nanomedicine is an interdisciplinary research field that results from the application of nanotechnology to medicine and has the potential to significantly improve some current treatments. Specifically, in the field of personalized medicine, it is expected to have a great impact in the near future due to its multiple advantages, namely its versatility to adapt a drug to a cohort of patients. In the present review, the properties and requirements of pharmaceutical dosage forms at the nanoscale, so-called nanomedicines, are been highlighted. An overview of the main current nanomedicines in pre-clinical and clinical development is presented, detailing the challenges to the personalization of these therapies. Next, the process of development of novel nanomedicines is described, from their design in research labs to their arrival on the market, including considerations for the design of nanomedicines adapted to the requirements of the market to achieve safe, effective, and quality products. Finally, attention is given to the point of view of the pharmaceutical industry, including regulation issues applied to the specific case of personalized medicine. The authors expect this review to be a useful overview of the current state of the art of nanomedicine research and industrial production, and the future opportunities of personalized medicine in the upcoming years. The authors encourage the development and marketing of novel personalized nanomedicines. Nanomedicina Nanotecnologia Assistència mèdica Indústria farmacèutica Nanomedicine Nanotechnology Medical care Pharmaceutical industry Personalized nanomedicine: a revolution at the nanoscale