2026-04-13T02:27:55Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1568172025-11-19T11:04:55Zcom_2072_1057col_2072_478917col_2072_478924

00925njm 22002777a 4500 dc Marhuenda-Muñoz, María author Laveriano-Santos, Emily P. author Tresserra i Rimbau, Anna author Lamuela Raventós, Rosa Ma. author Martínez Huélamo, Miriam author Vallverdú i Queralt, Anna author 2020-04-22T10:40:24Z 2020-04-22T10:40:24Z 2019-11-10 2020-04-22T10:40:24Z The role of gut microbiota in human health has been investigated extensively in recent years. The association of dysbiosis, detrimental changes in the colonic population, with several health conditions has led to the development of pro-, pre- and symbiotic foods. If not absorbed in the small intestine or secreted in bile, polyphenols and other food components can reach the large intestine where they are susceptible to modification by the microbial population, resulting in molecules with potentially beneficial health effects. This review provides an overview of studies that have detected and/or quantified microbial phenolic metabolites using high-performance liquid chromatography as the separation technique, followed by detection through mass spectrometry. Both in vitro experimental studies and human clinical trials are covered. Although many of the microbial phenolic metabolites (MPM) reported in in vitro studies were identified in human samples, further research is needed to associate them with clinical health outcomes. Microbiota intestinal Salut Polifenols Espectrometria de masses Cromatografia de líquids d'alta resolució Gastrointestinal microbiome Health Polyphenols Mass spectrometry High performance liquid chromatography Microbial Phenolic Metabolites: Which Molecules Actually Have an Effect on Human Health?