2026-04-13T12:31:59Zhttps://recercat.cat/oai/requestoai:recercat.cat:2445/1525232025-12-04T19:33:04Zcom_2072_1057col_2072_478908col_2072_478917col_2072_478933
RECERCAT
author
Pelay Gimeno, Marta
author
Tulla-Puche, Judit
author
Albericio Palomera, Fernando
2020-03-11T12:24:42Z2020-03-11T12:24:42Z2013-05-212020-03-11T12:24:43Z
Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as "head-to-side-chain" cyclodepsipeptides, have been isolated and characterized. These peptides present a unique structural arrangement that comprises a macrocyclic region closed through an ester bond between the C-terminus and a β-hydroxyl group, and terminated with a polyketide moiety or a more simple branched aliphatic acid. This structural pattern, the presence of unique and complex residues, and relevant bioactivity are the main features shared by all the members of this new class of depsipeptides, which are reviewed herein.
cc-by (c) Pelay Gimeno, Marta et al., 2013 http://creativecommons.org/licenses/by/3.0/es info:eu-repo/semantics/openAccess
Productes naturals
Medicaments peptídics
Poliquets
Natural products
Peptide drugs
Polychaeta
'Head-to-side-chain' cyclodepsipeptides of marine origin
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion