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oai:recercat.cat:2445/1399352025-12-04T21:00:41Zcom_2072_1057col_2072_478796col_2072_478917

Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platform García-Torres, José Gispert, C. Gómez, Elvira Vallés Giménez, Elisa Deposició (Metal·lúrgia) Electroquímica Hemoglobina Plating Electrochemistry Hemoglobin Three-dimensional porous Co-Ni films/alginate hybrid materials have been successfully prepared by electrodeposition to be used as a steerable magnetic device for drug delivery. Firstly, 3D porous Co-Ni films were prepared as substrates for the subsequent electrodeposition of the alginate biopolymer. Cyclic voltammetry, galvanostatic and potentiostatic studies were performed to establish the best conditions to obtain porous Co-Ni films. The electrochemical experiments were carried out in an electrolyte containing the metal salts and ammonium chloride at low pHs. In a second stage, the electrochemical deposition of alginate as a biocompatible polymer drug delivery carrier was performed. The characteristics of the alginate matrix were investigated in terms of electrochemical properties, morphology and drug release. The hybrid material obtained showed soft-magnetic behavior and drug release indicating its suitability to be used as a steerable magnetic drug delivery device. 2019-09-13T15:02:09Z 2019-09-13T15:02:09Z 2015 2019-09-13T15:02:09Z info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion 1463-9076 https://hdl.handle.net/2445/139935 644804 eng Versió postprint del document publicat a: https://doi.org/10.1039/C4CP04389H Physical Chemistry Chemical Physics, 2015, vol. 17, p. 1630-1636 https://doi.org/10.1039/C4CP04389H (c) García-Torres, José et al., 2015 info:eu-repo/semantics/openAccess 7 p. application/pdf Royal Society of Chemistry Articles publicats en revistes (Ciència dels Materials i Química Física)