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00925njm 22002777a 4500 dc Miralpeix, Montserrat author Decaux, Jean-François author Kahn, Axel author Bartrons Bach, Ramon author 2019-06-05T17:05:53Z 2019-06-05T17:05:53Z 1991-04 2019-06-05T17:05:53Z In primary culture of adult rat hepatocytes, vanadate in the presence of glucose stimulates the expression of the liver (L-type) pyruvate kinase gene. Glucose by itself was inactive, and vanadate, like insulin, was also inefficient in the absence of glucose. Similar results were obtained on glucokinase gene expression. An analogue of cAMP, 8-(4-chlorophenylthio)-cAMP, inhibited the production of L-type pyruvate kinase and glucokinase mRNAs in the presence of glucose plus vanadate. Micro RNAs Isoenzims Genètica Fetge Enzimologia Biosíntesi Farmacologia MicroRNAs Isoenzymes Genetics Liver Enzymology Biosynthesis Pharmacology Vanadate increases L-type pyruvate kinase mRNAs level in adult rat hepatocytes in primary culture