2026-04-17T05:50:34Zhttps://recercat.cat/oai/request
oai:recercat.cat:2445/1337252025-11-19T20:27:19Zcom_2072_1057col_2072_478822col_2072_478917
RECERCAT author Xu, Limei author Buldyrev, V. S. (Vladimir Sergeevich) author Stanley, H. Eugene (Harry Eugene), 1941- author Franzese, Giancarlo 2019-05-22T14:34:43Z2019-05-22T14:34:43Z2012-08-272019-05-22T14:34:43Z Several scenarios exist for the protein crystallization and aggregation in solutions near a metastable fluid-fluid phase separation below the solubility line. Based on computations, it was proposed that the fluid-fluid critical point enhances the crystallization rate by many orders of magnitude, while, based on experiments, it was proposed that the fluid-fluid spinodal controls the crystallization rate. Using molecular dynamic simulations for an isotropic model with sticky interaction, we show that neither of these scenarios adequately describes the crystallization mechanism near a metastable fluid-fluid phase separation. We find that the emergence of the high-density fluid inside the spinodal drastically enhances the crystal nucleation in the subcritical region following Ostwald's rule of stages. (c) American Physical Society, 2012 info:eu-repo/semantics/openAccess Física de partícules Experiments Particle physics Experiments Homogeneous Crystal Nucleation Near a Metastable Fluid-Fluid Phase Transition info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion