2026-04-17T05:14:11Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1281982025-12-05T14:25:28Zcom_2072_1057col_2072_478816col_2072_478917

00925njm 22002777a 4500 dc Coussanes, Guilhem author Jakobi, Harald author Lindell, Stephen author Bonjoch i Sesé, Josep author 2019-02-13T11:17:03Z 2019-05-16T05:10:17Z 2018-05-16 2019-02-13T11:17:03Z A cyanoborohydride-promoted radical cyclization methodology has been developed to access α-chlorolactams in a simple and efficient way, using NaBH3CN and trichloroacetamides easily available from allylic and homoallylic secondary amines. This methodology allowed the synthesis of a library of αchlorolactams (mono and bicyclic), which were tested for herbicidal activity, trans-3-chloro-4-methyl-1-(3-trifluoromethyl)phenyl-2-pyrrolidinone being the most active. Lactames Herbicides Radicals (Química) Síntesi orgànica Lactams Herbicides Radicals (Chemistry) Organic synthesis Synthesis of a-chlorolactams by cyanoborohydride-mediated radical cyclization of trichloroacetamides