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A proposal of an effective platelet-rich plasma protocol for the treatment of androgenetic alopecia Ferrando, Juan García García, Sandra C. González de Cossío, Ana C. Bou, Lola Navarra, Esperanza Alopècia Malalties del cabell Plasma sanguini Baldness Hair diseases Blood plasma Background: Platelet-rich plasma (PRP) has emerged as a promising treatment for androgenetic alopecia (AGA). In spite of the several studies previously reported, to date, a standardized protocol for PRP preparation and application, as well as a standard method for evaluating results has not been established. Aims: The aim of this study is to propose a standardized method for preparation and application of PRP for male AGA (MAGA) and female AGA (FAGA) and assess its safety and efficacy as a co-adjuvant therapy. Materials and Methods: Seventy-eight patients, 19 men and 59 women with AGA Grades II-IV in Ebling's scale, currently on treatment with topical minoxidil and/or oral finasteride for more than a year without improvement, were included in this study. PRP was prepared using a single spin method, and injected in affected areas for 3 monthly sessions, followed by 3 bimonthly sessions. A decrease of at least one grade in Ebling's scale was considered a successful result. Results: After the 6° session, 71.4% of MAGA and 73.4% of FAGA patients reached a successful outcome while 21.4% and 16.3%, respectively, remained without changes. Only 7.1% of MAGA and 10.2% of FAGA presented worsening of their condition. Conclusions: PRP together with a periodical application protocol can be considered effective as a coadjuvant therapy in patients who no longer respond to pharmacological treatments. Ebling's scale was a practical and reliable parameter to allow a better evaluation in both MAGA and FAGA. 2019-01-23T14:49:23Z 2019-01-23T14:49:23Z 2017-10 2019-01-23T14:49:24Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 0974-7753 https://hdl.handle.net/2445/127568 675446 29118521 eng Reproducció del document publicat a: https://doi.org/10.4103/ijt.ijt_27_17 International Journal of Trichology, 2017, vol. 9, num. 4, p. 165-170 https://doi.org/10.4103/ijt.ijt_27_17 cc-by-nc-sa (c) Ferrando, Juan et al., 2017 http://creativecommons.org/licenses/by-nc-sa/3.0/es info:eu-repo/semantics/openAccess 7 p. application/pdf Medknow Publications Articles publicats en revistes (Medicina)