2026-04-17T04:11:04Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1273222025-12-04T22:47:23Zcom_2072_1057col_2072_478825col_2072_478917

Modulació de la inducció del sistema d'emergència (SOS) en Escherichia coli per la regío amino-terminal de la proteïna RecA. Barbé García, Jordi Sala, Montserrat Llagostera, Montserrat Guerrero, Ricardo, 1943- Duplicació de l'ADN Escheríchia coli Reparació de l'ADN DNA replication Escherichia coli DNA repair The amino-terminal fragment of the RecA protein was cloned in pUA27 plasmid and introduced in different repair mutants of Escherichia coli. The UV-mediated induction of several SOS functions was then studied. Results show that the truncated RecA protein plays an important role in the UV-damaged DNA when the level of the chromosomal RecA protein is low. Furthermore, RecA protein inhibited the protease activity of the wild type RecA protein causing a decrease in the SOS system induction. All these data suggest that hybrid tetramers between both truncated and wild type RecA proteins may be formed, and as a consequence the ATPase capacity and active conformation of the wild type RecA protein are blocked. 2019-01-16T11:06:48Z 2019-01-16T11:06:48Z 1989 2019-01-16T11:06:48Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://www.raco.cat/index.php/TreballsSCBiologia/article/view/238113/ Treballs de la Societat Catalana de Biologia, 1989, vol. 40, p. 33-46 cc-by-nc-nd (c) Barbé García, Jordi et al., 1989 http://creativecommons.org/licenses/by-nc-nd/3.0/es info:eu-repo/semantics/openAccess Societat Catalana de Biologia Articles publicats en revistes (Genètica, Microbiologia i Estadística)