2026-04-19T09:43:17Zhttps://recercat.cat/oai/requestoai:recercat.cat:2445/1270152025-12-04T21:42:12Zcom_2072_1057col_2072_478917col_2072_478933
RECERCAT
author
Salomó i Prat, Ernest
author
Gallen Ortiz, Albert
author
Sciortino, Giuseppe
author
Ujaque, Gregori
author
Grabulosa, Arnald
author
Lledós, Agustí (Lledós i Falcó)
author
Riera i Escalé, Antoni
author
Verdaguer i Espaulella, Xavier
2018-12-17T14:54:57Z2019-11-26T06:10:15Z2018-11-262018-12-17T14:54:58Z
A novel cationic [IrH(THF)(P,N)(imine)] [BArF] catalyst contg. a P-stereogenic MaxPHOX ligand is described for the direct asym. hydrogenation of N-Me and N-alkyl imines. This is the first catalytic system to attain high enantioselectivity (up to 94% ee) in this type of transformation. The labile THF ligand allows for effective activation and reactivity, even at low temps. D. functional theory calcns. allowed the rationalization of the stereochem. course of the reaction.
(c) American Chemical Society , 2018 info:eu-repo/semantics/openAccess
Catàlisi asimètrica
Lligands
Hidrogenació
Enantioselective catalysis
Ligands
Hydrogenation
Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst
info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion