2026-04-17T07:36:45Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1270152025-12-04T21:42:12Zcom_2072_1057col_2072_478917col_2072_478933

00925njm 22002777a 4500 dc Salomó i Prat, Ernest author Gallen Ortiz, Albert author Sciortino, Giuseppe author Ujaque, Gregori author Grabulosa, Arnald author Lledós, Agustí (Lledós i Falcó) author Riera i Escalé, Antoni author Verdaguer i Espaulella, Xavier author 2018-12-17T14:54:57Z 2019-11-26T06:10:15Z 2018-11-26 2018-12-17T14:54:58Z A novel cationic [IrH(THF)(P,N)(imine)] [BArF] catalyst contg. a P-stereogenic MaxPHOX ligand is described for the direct asym. hydrogenation of N-Me and N-alkyl imines. This is the first catalytic system to attain high enantioselectivity (up to 94% ee) in this type of transformation. The labile THF ligand allows for effective activation and reactivity, even at low temps. D. functional theory calcns. allowed the rationalization of the stereochem. course of the reaction. Catàlisi asimètrica Lligands Hidrogenació Enantioselective catalysis Ligands Hydrogenation Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst