2026-04-13T01:50:54Zhttps://recercat.cat/oai/request
oai:recercat.cat:2445/1253022025-11-19T20:27:06Zcom_2072_1057col_2072_478822col_2072_478917
RECERCAT author Alert Zenón, Ricard author Casademunt i Viader, Jaume author Brugués, Jan author Sens, Pierre 2018-10-15T11:30:44Z2018-10-15T11:30:44Z2015-04-212018-10-15T11:30:44Z We propose a model for membrane-cortex adhesion which couples membrane deformations, hydrodynamics and kinetics of membrane-cortex ligands. In its simplest form, the model gives explicit predictions for the critical pressure for membrane detachment and for the value of adhesion energy. We show that these quantities exhibit a significant dependence on the active acto-myosin stresses. The model provides a simple framework to access quantitative information on cortical activity by means of micropipette experiments. We also extend the model to incorporate fluctuations and show that detailed information on the stability of membrane-cortex coupling can be obtained by a combination of micropipette aspiration and fluctuation spectroscopy measurements. (c) Biophysical Society, 2015 info:eu-repo/semantics/openAccess Lligands Models biològics Viscositat Membranes cel·lulars Ligands Biological models Viscosity Cell membranes Model for probing membrane-cortex adhesion by micropipette aspirations and fluctuation spectroscopy info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion