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oai:recercat.cat:2445/1244642025-12-20T03:37:48Zcom_2072_1057col_2072_478799col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Egea, Javier author Fabregat Romero, Isabel author Frapart, Yves M. author Ghezzi, Pietro author Görlach, Agnes author Kietzmann, Thomas author Kubaichuk, Kateryna author Knaus, Ulla G. author Lopez, Manuela G. author Olaso Gonzalez, Gloria author Petry, Andreas author Berndt, Carsten author Bernlohr, David author Bertran Rodríguez, Esther author Korac, Bato author Bindoli, Alberto author Miguel, Verónica author Giricz, Zoltán author Bottari, Serge P. author Brito, Paula M. author Carrara, Guia author Krieg, Thomas author Casas, Ana I. author Hillion, Melanie author Cuadrado, Antonio author Chatzi, Afroditi author Görbe, Anikó author Dang, Pham My-Chan author Dunn, Joe Dan author Korkmaz, Kemal Sami author Pavicevic, A author Edson, Amanda J. author Laranjinha, João author Assar, Mariam El author El-Benna, Jamel author Ferdinandy, Péter author Monsalve, María author Fernandes, Ana S. author Koziel, Rafal author Griffiths, Helen author Fladmark, Kari E. author Hampl, Vaclav author Hanf, Alina author Lazou, Antigone author Huang, Jingjing author Mikhed, Yuliya author Kračun, Damir author Ilikay, Serap author Mouthuy, Pierre-Alexis author Jansen-durr, P author Jaquet, Vincent author Joles, Jaap A. author Prieto, Ignacio author Kalyanaraman, Balaraman author Smith, Geoffrey L. author Milisav, Irina author Kaminskyy, Danylo author Karbaschi, Mahsa author Kleanthous, Marina author Klotz, Lars-Oliver author Mulvey, John author Krause, Karl-Heinz author Pedre, Brandán author Milković, Lidija author Křen, Vladimír author Li, Huige author Rigobello, Maria Pia author Valentová, Kateřina author Peyrot, Fabienne author Martínez Ruiz, Antonio author Matsui, Reiko author McBean, Gethin J. author Steinbrenner, Holger author Meredith, Stuart P. author Robledinos Antón, Natalia author Miranda Vizuete, Antonio author Messens, Joris author Phylactides, Marios author Mojović, Miloš author Münzel, Thomas author Soldati, Thierry author Schulz, Rainer author Muzykantov, Vladimir author Stepanić, Višnja author Nguyen, Isabel T.N. author Oelze, Matthias author d'Oliveira, Nuno Gustavo author Žarković, Neven author Palmeira, Carlos M. author Sousa, Bebiana C. author Pircalabioru, Gratiela G. author Papaevgeniou, Nikoletta author Pitt, Andrew R. author Poulsen, Henrik E. author Steven, Sebastian author Rodríguez Mañas, Leocadio author Breusegem, Frank Van author Spickett, Corinne M. author Rolo, Anabela P. author Zatloukalová, Martina author Rousset, Francis author Ruskovska, Tatjana author Saraiva, Nuno author Antelmann, Haike author Sasson, Shlomo author Chondrogianni, Niki author Varisli, Lokman author Schröder, Katrin author Semen, Khrystyna author Seredenina, Tamara author Shakirzyanova, Anastasia author Zielonka, Jacek author Stancic, Ana author Vina, Jose author Veal, Elizabeth A. author Stasia, Marie José author Tokatlidis, Kostas author Antunes, Fernando author Förstermann, Ulrich author Winyard, Paul author Tuncay, Erkan author Turan, Belma author Ursini, Fulvio author Smet, Barbara De author Vacek, Jan author Aslan, Mutay author Yalçın, A. Suha author Vajnerova, Olga author Abbas, Kahina author Yelisyeyeva, Olha author Touyz, Rhian M. author Conrad, Marcus author Bachschmid, Markus M. author Papapetropoulos, Andreas author Debelec-Butuner, Bilge author Grune, Tilman author Lamas, Santiago author Schmidt, Harald H. H. W. author Herget, Jan author Lisa, Fabio Di author Cooke, Marcus S. author Ademowo, Opeyemi S. author Daiber, Andreas author Afonso, Catarina B. author Andreadou, Ioanna author Dias, Irundika H.K. author Barbosa de Figueiredo, Rui Pedro author Giniatullin, Rashid author Costa, João G. author Belousov, Vsevolod author Hernansanz Agustín, Pablo author 2018-09-12T09:54:03Z 2018-09-12T09:54:03Z 2017-10-01 2018-07-24T11:59:58Z The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. This report highlights the major achievements of EU-ROS as well as research updates and new perspectives arising from its members. The EU-ROS consortium comprised more than 140 active members who worked together for four years on the topics briefly described below. The formation of reactive oxygen and nitrogen species (RONS) is an established hallmark of our aerobic environment and metabolism but RONS also act as messengers via redox regulation of essential cellular processes. The fact that many diseases have been found to be associated with oxidative stress established the theory of oxidative stress as a trigger of diseases that can be corrected by antioxidant therapy. However, while experimental studies support this thesis, clinical studies still generate controversial results, due to complex pathophysiology of oxidative stress in humans. For future improvement of antioxidant therapy and better understanding of redox-associated disease progression detailed knowledge on the sources and targets of RONS formation and discrimination of their detrimental or beneficial roles is required. In order to advance this important area of biology and medicine, highly synergistic approaches combining a variety of diverse and contrasting disciplines are needed. Estrès oxidatiu Antioxidants Oxidative stress European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)