2026-04-14T02:58:08Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1242782025-12-05T12:08:57Zcom_2072_1057col_2072_478916col_2072_478917

urn:hdl:2445/124278 Actinic Keratosis, a Chronic, Progressive Disease: Understanding Clinical Gaps to Optimise Patient Management Cerio, Rino Dirschka, Thomas Dréno, Brigitte Figueras Nart, Ignasi Lear, John T. Pellacani, Giovanni Peris, Ketty Ruiz de Casas, Andrés Tumors Malalties de la pell Skin diseases Actinic keratosis (AK) is a chronic, progressive disease of the skin that has undergone long-term sun exposure. The affected areas contain visible and subclinical nonvisible sun damage resulting in epidermal keratinocyte dysplasia, known by many as ‘field cancerisation’ (1), which is prone to AKs and sun-related skin cancer (2). Thus, visible AKs are clinical biomarkers for a photo-damaged field with subclinical damage associated with the unpredictable risk of progression to invasive squamous cell carcinoma (iSCC) (3). The aim of this multiexpert opinion article is to provide a discussion succinctly highlighting the clinical gaps for optimal management of AK: the lack of a universal definition and the need for a standardised grade assessment of AK/field cancerisation that also takes into account individual risk. 2018-09-05T07:57:46Z 2018-09-05T07:57:46Z 2017-09-01 2018-07-24T12:01:41Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.2340/00015555-2692 Acta Dermato-Venereologica, 2017, vol. 97, num. 8, p. 997-998 https://doi.org/10.2340/00015555-2692 cc by-nc (c) Acta Dermato-Venereologica, 2017 http://creativecommons.org/licenses/by-nc/3.0/es/ info:eu-repo/semantics/openAccess Acta Dermato-Venereologica Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))