2026-04-17T03:55:38Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1238442025-12-05T09:41:40Zcom_2072_1057col_2072_478778col_2072_478917

00925njm 22002777a 4500 dc Pons-Salort, Margarita author Serra Cobo, Jordi author Jay, Flora author López-Roig, Marc author Lavenir, Rachel author Guillemot, Didier author Letort, Véronique author Bourhy, Hervé author Opatowski, Lulla author 2018-07-24T09:39:46Z 2018-07-24T09:39:46Z 2014-04-22 2018-07-24T09:39:46Z Rabies is a worldwide zoonosis resulting from Lyssavirus infection. In Europe, Eptesicus serotinus is the most frequently reported bat species infected with Lyssavirus, and thus considered to be the reservoir of European bat Lyssavirus type 1 (EBLV-1). To date, the role of other bat species in EBLV-1 epidemiology and persistence remains unknown. Here, we built an EBLV-1−transmission model based on local observations of a three-cave and four-bat species (Myotis capaccinii, Myotis myotis, Miniopterus schreibersii, Rhinolophus ferrumequinum) system in the Balearic Islands, for which a 1995-2011 serological dataset indicated the continuous presence of EBLV-1. Eptesicus serotinus was never observed in the system during the 16-year follow-up and therefore was not included in the model. We used the model to explore virus persistence mechanisms and to assess the importance of each bat species in the transmission dynamics. We found that EBLV-1 could not be sustained if transmission between M. schreibersii and other bat species was eliminated, suggesting that this species serves as a regional reservoir. Global sensitivity analysis using Sobol's method revealed that following the rate of autumn−winter infectious contacts, M. schreibersii's incubation- and immune-period durations, but not the infectious period length, were the most relevant factors driving virus persistence. Ratapinyades Virus Colònies animals Bats Viruses Animal colonies Insights into Persistence Mechanisms of a Zoonotic Virus in Bat Colonies Using a Multispecies Metapopulation Model.