2026-04-13T05:55:33Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1220772025-11-19T11:04:07Zcom_2072_1057col_2072_478917col_2072_478924

00925njm 22002777a 4500 dc García-Conesa, María Teresa author Chambers, Karen author Combet, Emilie author Pinto, Paula author Garcia Aloy, Mar author Andrés Lacueva, Ma. Cristina author Pascual Teresa, Sonia de author Mena, Pedro author Konic Ristic, Aleksandra author Hollands, Wendy J. author Kroon, Paul A. author Rodriguez-Mateos, Ana author Istas, Geoffrey author Kontogiorgis, Christos A. author Rai, Dilip K. author Gibney, Eileen R. author Morand, Christine author Espín, Juan Carlos author González-Sarrías, Antonio author 2018-05-04T09:50:29Z 2018-05-04T09:50:29Z 2018-02-28 2018-05-04T09:50:29Z Understanding interindividual variability in response to dietary polyphenols remains essential to elucidate their effects on cardiometabolic disease development. A meta-analysis of 128 randomized clinical trials was conducted to investigate the effects of berries and red grapes/wine as sources of anthocyanins and of nuts and pomegranate as sources of ellagitannins on a range of cardiometabolic risk biomarkers. The potential influence of various demographic and lifestyle factors on the variability in the response to these products were explored. Both anthocyanin- and ellagitannin-containing products reduced total-cholesterol with nuts and berries yielding more significant effects than pomegranate and grapes. Blood pressure was significantly reduced by the two main sources of anthocyanins, berries and red grapes/wine, whereas waist circumference, LDL-cholesterol, triglycerides, and glucose weremost significantly lowered by the ellagitannin-products, particularly nuts. Additionally, we found an indication of a small increase in HDL-cholesterol most significant with nuts and, in flow-mediated dilation by nuts and berries. Most of these effects were detected in obese/overweight people but we found limited or non-evidence in normoweight individuals or of the influence of sex or smoking status. The effects of other factors, i.e., habitual diet, health status or country where the study was conducted, were inconsistent and require further investigation. Antocianines Sistema cardiovascular Vi negre Raïms Fruita seca Anthocyanins Cardiovascular system Red wines Grapes Dried fruit Meta-analysis of the efficacy of ellagitannin- and anthocyanin-containing products at modifying cardiometabolic biomarkers: factors influencing variability of the individual responses