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Leukemoid Reaction: Presentation of Two Cases Habimana Jordana, N Anna Arca Díaz, Gemma Botet Mussons, Francisco Estudi de casos Hematologia pediàtrica Case studies Pediatric hematology The leukemoid reaction is defined by the presence in peripheral blood of white cells above 50,000/mm3 or neutrophils above 30,000/mm3 . The frequency varies between 1.3 and 15% of newborns admitted to neonatal intensive care units [1]. It usually appears during the first two weeks of life and more frequently during the first four days, the duration is about 8.5 days [2]. In extremely premature, this process is produced by an inflammatory response that active cytokines who increased granulocyte colony-stimulating factors (G-CSF). These induce the production of neutrophils that cause hyperleukocytosis. 2017-10-05T17:17:19Z 2017-10-05T17:17:19Z 2017-08-25 2017-10-05T17:17:19Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.16966/2471-4925.149 Journal of Clinical Case Studies, 2017, vol. 2, num. 4 https://doi.org/10.16966/2471-4925.149 cc-by (c) Habimana Jordana, N Anna et al., 2017 http://creativecommons.org/licenses/by/3.0/es info:eu-repo/semantics/openAccess Sci Forschen Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)