2026-04-17T23:54:14Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1141902025-12-10T00:40:57Zcom_2072_1057col_2072_478917

Respiratory microbiota and lower respiratory tract disease Lanaspa, Miguel Bassat Orellana, Quique Medeiros, Marcia Melo Muñoz-Almagro, Carmen Malalties de l'aparell respiratori Bacteris Respiratory organs diseases Bacteria INTRODUCTION: The respiratory airways harbor a complex succession of ecological niches with distinct but related bacterial communities. Particular challenges of respiratory microbiome research have led to limited scientific output compared to other human microbiomes. Areas covered: In this review, we summarize the current state of knowledge of the bacterial respiratory microbiome, with a particular focus on associations between the respiratory microbiome and lower respiratory tract conditions. Expert commentary: There is growing evidence that the respiratory microbiome is associated with lower respiratory infectious diseases and related conditions. Most respiratory microbiome reports are metataxonomic cross-sectional or case-control studies with relatively small sample sizes. Large, prospective projects with metatranscriptomics or metabolomics approach are needed to unravel the effect of the respiratory microbiome on health-related conditions. Moreover, standardization in sampling, library preparation, sequencing techniques and data analysis should be encouraged. 2017-07-21T12:10:35Z 2018-07-07T22:01:21Z 2017-07-07 2017-07-19T18:00:17Z info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion 1478-7210 1478-7210 https://hdl.handle.net/2445/114190 eng Reproducció del document publicat a: http://dx.doi.org/10.1080/14787210.2017.1349609 Expert Review of Anti-Infective Therapy, 2017, vol. 15, num. 7, p. 703-711 http://dx.doi.org/10.1080/14787210.2017.1349609 (c) Taylor & Francis , 2017 info:eu-repo/semantics/openAccess 20 p. application/pdf Taylor & Francis Articles publicats en revistes (ISGlobal)