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oai:recercat.cat:2445/1074962025-12-06T03:22:50Zcom_2072_1057col_2072_478801col_2072_478916col_2072_478917

The longitudinal association between a discrepancy measure of anosognosia in patients with dementia, caregiver burden and depression Perales-Puchalt, Jaime Turró-Garriga, Oriol Gascón-Bayarri, Jordi Reñé Ramírez, Ramon Conde Sala, Josep Lluís Malaltia d'Alzheimer Depressió psíquica Cuidadors Alzheimer's disease Mental depression Caregivers Background: According to cross-sectional studies, there is an association between anosognosia in people with dementia and caregiver's burden and depression. Anosognosia in patients may be a cause of caregiver burden and depression. However, variability in caregiver anosognosia ratings may exist as caregivers with burden and depression may have a more pessimistic view of the patients' health. Objective: to assess the variability of caregiver anosognosia ratings of patients with dementia using a widely used anosognosia scale and its longitudinal relationship with caregiver burden and depression. Methods: A convenience cohort of 221 consecutive dementia outpatient and caregiver dyads was followed up at 12 and 24 months. The main instruments used were the Anosognosia Questionnaire-Dementia (AQ-D), Caregiver Burden Interview, and Geriatric Depression Scale. Linear mixed models were used including time as a factor in every model. Multivariate analyses controlled for caregiver's socio-demographic and possible confounding factors. Results: Attrition at 12 and 24 months was 24.9% and 42.5% respectively. Patients at baseline were on average 77.8 years of age, 63.3% were women, and 63.3% had <5 years of education. In the bivariate analyses, caregiver burden, depression, and gender were associated with caregiver ratings of total, cognitive, and personality AQ-D of the patient at different time points. Multivariate analyses revealed burden as the caregiver variable most consistently associated with total, cognitive, and personality caregiver AQ-D ratings of the patient. Conclusion: Some caregiver characteristics, especially burden, are associated with caregiver ratings of AQ-D with regard to the patient. 2017-02-27T19:00:00Z 2017-02-27T19:00:00Z 2016-04-27 2017-02-27T19:00:00Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.3233/JAD-160065 Journal of Alzheimer's Disease, 2016, vol. 53, num. 3, p. 1133-1143 https://doi.org/10.3233/JAD-160065 (c) Perales-Puchalt, J. et al., 2016 info:eu-repo/semantics/openAccess IOS Press Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació)