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               <dc:title>Adherence to Childhood Tuberculosis Treatment in Mozambique</dc:title>
               <dc:creator>López Varela, Elisa</dc:creator>
               <dc:creator>Sequera Buzarquis, Victor Guillermo</dc:creator>
               <dc:creator>García-Basteiro, Alberto L.</dc:creator>
               <dc:creator>Augusto, Orvalho</dc:creator>
               <dc:creator>Munguambe, Khátia</dc:creator>
               <dc:creator>Sacarlal, Jahit</dc:creator>
               <dc:creator>Alonso, Pedro</dc:creator>
               <dc:subject>Infància</dc:subject>
               <dc:subject>Tuberculosi</dc:subject>
               <dc:subject>Moçambic</dc:subject>
               <dc:subject>Childhood</dc:subject>
               <dc:subject>Tuberculosis</dc:subject>
               <dc:subject>Mozambique</dc:subject>
               <dc:description>BACKGROUND: There is limited literature regarding adherence&#xd;
                rates for the treatment of tuberculosis (TB) in children. We&#xd;
                aimed to describe TB treatment outcomes and adherence as well as&#xd;
                to evaluate associated factors to poor adherence in Mozambican&#xd;
                children. METHODS: This is a sub-study of a community TB&#xd;
                incidence study among children &lt;3 years of age. Incomplete&#xd;
                adherence included the sum of lost-to-follow-up cases plus those&#xd;
                with a delay of > 3 weeks to treatment completion. RESULTS:&#xd;
                Fifty TB treatments were assessed. Forty-four (88.0%) patients&#xd;
                completed treatment, two (4.0%) died during treatment and four&#xd;
                (8.0%) were lost to follow-up. Incomplete adherence was observed&#xd;
                in 31.3% (15 of 48) of cases and was associated with&#xd;
                malnutrition or history of a migrant mother. CONCLUSION:&#xd;
                Although treatment outcome is overall good, there is still a&#xd;
                significant proportion of incomplete adherence. Further larger&#xd;
                paediatric TB cohorts and qualitative approaches are needed to&#xd;
                assess and confirm potential factors for non-adherence.</dc:description>
               <dc:date>2016-09-08T09:53:35Z</dc:date>
               <dc:date>2017-08-12T22:01:35Z</dc:date>
               <dc:date>2016-08-12</dc:date>
               <dc:date>2016-09-07T18:00:22Z</dc:date>
               <dc:type>info:eu-repo/semantics/article</dc:type>
               <dc:type>info:eu-repo/semantics/acceptedVersion</dc:type>
               <dc:relation>Versió postprint del document publicat a:&#xd;
                http://dx.doi.org/10.1093/tropej/fmw048</dc:relation>
               <dc:relation>Journal of Tropical Pediatrics, 2016</dc:relation>
               <dc:relation>http://dx.doi.org/10.1093/tropej/fmw048</dc:relation>
               <dc:rights>(c) López-Varela et al., 2016</dc:rights>
               <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
               <dc:publisher>Oxford University Press</dc:publisher>
               <dc:source>Articles publicats en revistes (ISGlobal)</dc:source>
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