2026-04-13T00:48:28Zhttps://recercat.cat/oai/request

oai:recercat.cat:2117/891042026-01-18T08:27:35Zcom_2072_1033col_2072_452950

Bio-nanohybrid catalysts based on L-leucine immobilized in hydrotalcite and their activity in aldol reaction Crivoi, Dana-Georgiana Miranda, Ronald Alexander Finocchio, Elisabetta Llorca Piqué, Jordi Ramis, Gianguido Sueiras, Jesus Eduardo Segarra González, Anna Maria Medina Mena, Francisco Àrees temàtiques de la UPC::Enginyeria química::Química física Nanotechnology Catalysts Catalysis Chemistry, Physical and theorical Asymmetric catalysis Hydrotalcite Immobilization L-Leucine Nanohybrid materials Layered double hydroxides Amino-acids Intercalation Clays Water Montmorillonite Coprecipitation Reconstruction Spectroscopy Precursors Nanotecnologia Catalitzadors Catàlisi Fisicoquímica Nanohybrid materials based on L-leucine (L-Leu) and hydrotalcites (HT) were prepared by the ion exchange and reconstruction method, under mild synthesis conditions. The location, amount and the form of the immobilized L-Leu are affected not only by the time of synthesis, but also by temperature and ultrasound treatment. The XRD results demonstrate that the immobilization occurs in either a vertical or oblique orientation with respect to the HT layers. The catalytic activity of these materials was tested in the aldol addition reaction of cyclohexanone with different aromatic aldehydes, affording mainly the syndiastereomer.. Furthermore, the present study demonstrates that both diastereo- and enantioselectivity can be easily modulated by the appropriate combination of nanohybrid catalyst, solvent and reaction time. (C) 2016 Elsevier B.V. All rights reserved. Postprint (author's final draft) 2016-06-05 Article http://creativecommons.org/licenses/by-nc-nd/3.0/es/ Open Access