2026-04-13T01:31:47Zhttps://recercat.cat/oai/request

oai:recercat.cat:2117/4389372026-01-24T13:38:54Zcom_2072_1033col_2072_452950

00925njm 22002777a 4500 dc Molins Pitarch, Carla author Khao, Jonathan author Bonet, Santiago author Justicia, Yolanda author Altube, Clementina author Goodstadt, Mike author Ribot Puntí, Francesc author Aiden, Erez Lieberman author Neretti, Nicola author McGill, Gaël G. author Martí Renom, Marc A. author 2025-06-26 Advances in the feld of three-dimensional (3D) genomics have revealed an everexpanding array of architectural features that were unknown only a few years ago. Just as ribbon diagrams integrate spatial and symbolic representation to communicate the shape of a protein, the representation of genomes in 3D space requires the devel- opment and use of new cartographic symbols and visual conventions. Here, we pro- pose a conceptualized grammar that makes it easier to create visual 3D representations of genomes. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Sklodowska-Curie grant agreement No 823327 to M.A.M-R. and F.R. M.A.M-R. also acknowledges support by the Spanish Ministerio de Ciencia e Innovación (PID2020-115696RB-I00 and PID2023-151484NB-I00). M.A.M-R., E.L.A., and N.N. acknowledge support by the National Human Genome Research Institute of the National Institutes of Health under Award Number RM1HG011016. The content is solely the responsibility of the authors and does not necessarily represent the ofcial views of the National Institutes of Health. Peer Reviewed Postprint (published version) Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica Human genome Genomics Three-dimensional imaging Genòmica Genoma humà Imatgeria tridimensional Geometric diagrams of genomes: constructing a visual grammar for 3D genomics