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oai:recercat.cat:2117/3869742026-02-07T12:14:07Zcom_2072_1033col_2072_452950

Kinetic model of photo-Fenton degradation of paracetamol in an annular reactor: main reaction intermediates and cytotoxicity studies Giménez, Bárbara N. Conte, Leandro Oscar Audino, Francesca Schenone, Agustina Graells Sobré, Moisès Alfano, Orlando Mario Pérez Moya, Montserrat Universitat Politècnica de Catalunya. Departament d'Enginyeria Química Universitat Politècnica de Catalunya. ENCORE - Energy Catalysis Process Reaction Engineering Àrees temàtiques de la UPC::Enginyeria química Acetaminophen Photo-Fenton Cytotoxicity Hydroquinone LVRPA 1 4-benzoquinone Citotoxicitat A kinetic model derived from a simplified reaction sequence is proposed for the photo-Fenton degradation of Paracetamol (PCT), employing an annular photoreactor. The kinetic model explicitly included the effects of radiation absorption on pollutant degradation kinetics through the evaluation of the Local Volumetric Rate of Photon Absorption (LVRPA). Irradiated experiments achieved an average PCT conversion of 99.3% at 5 min of reaction, and a maximum of 69% of mineralization. Conversely, non-irradiated experiments reached an average PCT conversion of 86.6% at 5 min of reaction, and a maximum of 35% of mineralization. Kinetic parameters (, ,M-1s-1) were estimated employing a nonlinear, multi-parameter regression method, and the validated kinetic model was used to predict temporal variations of the concentrations of HP, PCT, and the main reaction intermediates: hydroquinone (HQ) and 1,4-benzoquinone (BQ). The root mean square error (RMSE) values obtained for HP, PCT, HP, HQ and BQ were 1.16¿×¿10-2, 7.13¿×¿10-1, 3.53¿×¿10-3, 3.05¿×¿10-3 mM, respectively, showing a good agreement between experimental and predicted data. Moreover, the kinetic model was validated with a new set of experimental tests, confirming its predictive capacity. Beyond the degree of mineralization attained, additional cytotoxicity tests proved that the photo-Fenton process is effective in generating a non-toxic effluent under the operating variables investigated. Peer Reviewed Postprint (published version) 2023-03-03 Article Giménez, B. [et al.]. Kinetic model of photo-Fenton degradation of paracetamol in an annular reactor: main reaction intermediates and cytotoxicity studies. "Catalysis today", 3 Març 2023, vol. 413-415, núm. article 113958. 0920-5861 https://hdl.handle.net/2117/386974 10.1016/j.cattod.2022.11.019 eng https://www.sciencedirect.com/science/article/pii/S0920586122004473 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-116051RB-I00/ES/IMPLANTACION DE LA ECONOMIA CIRCULAR EN LA INDUSTRIA DE PROCESO (CEPI): METODOS Y HERRAMIENTAS PARA LA INTEGRACION CIRCULAR DE SISTEMAS/ http://creativecommons.org/licenses/by-nc-nd/4.0/ Open Access Attribution-NonCommercial-NoDerivatives 4.0 International application/pdf