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oai:recercat.cat:2117/3500332026-02-11T06:32:17Zcom_2072_1033col_2072_452950

Robust polytopic-LPV body-weight-dependent control of blood glucose in type-1 diabetes Vafamand, Navid Asemani, Mohammad Hassan Mobayen, Saleh Pujol Vázquez, Gisela Universitat Politècnica de Catalunya. Departament de Matemàtiques Universitat Politècnica de Catalunya. CoDAlab - Control, Modelització, Identificació i Aplicacions Àrees temàtiques de la UPC::Informàtica::Automàtica i control Blood sugar -- Control -- Mathematical models Programmable controllers Bergman model Body-weight effect Dynamic output controller Glucose-insulin system Linear parameter varying (LPV) model. Glucèmia -- Control - Models matemàtics Controladors programables This paper presents a robust H8 polytopic Linear Parameter Varying (LPV) controller to reg- ulate the blood glucose level in type-1 diabetes patients. The suggested approach utilizes an observer-based controller and polytopic inexact gain-scheduling scheme to construct the stabilizing injecting insulin resilient against the external meal and snack disturbance in Silico. To assure the closed-loop stability and prescribed H8 performance, a Quadratic Lyapunov Function (QLF) is used and the stabilization conditions are derived in terms of Linear Matrix Inequalities (LMIs). The conventional minimal Bergman model is improved by considering the effect of body-weight on the glucose-insulin phenomenon and the new body-weight functions are identified based on real data. Then, for the body-weight-dependent Bergman model, a polytopic-LPV model is obtained. Simulations show the advantages of the developed glucose-insulin model and the robustness of the suggested controller in dealing with the effects of a meal for patients with different weights and avoiding hypoglycemia and hyperglycemia disorders. Peer Reviewed Postprint (published version) 2021-07 Article Vafaman, N. [et al.]. Robust polytopic-LPV body-weight-dependent control of blood glucose in type-1 diabetes. "IEEE access", Juliol 2021, vol. 9, p. 96367-96379. 2169-3536 https://hdl.handle.net/2117/350033 10.1109/ACCESS.2021.3095216 eng https://ieeexplore.ieee.org/document/9475530 https://creativecommons.org/licenses/by/4.0/ Open Access Attribution 4.0 International 13 p. application/pdf Institute of Electrical and Electronics Engineers (IEEE)