2026-04-17T02:13:32Zhttps://recercat.cat/oai/request

oai:recercat.cat:2117/3323212025-07-17T05:24:54Zcom_2072_1033col_2072_452950

3D skin microfluidic phantom for in vitro wearable testing Rabost Garcia, Genís Carreras Gallo, Óscar Colmena, Valeria Aguilar, Javier Punter Villagrasa, Jaime Muñoz Pascual, Francesc Xavier Farré Lladós, Josep Casals Terré, Jasmina Àrees temàtiques de la UPC::Enginyeria mecànica::Mecànica de fluids Skin Perspiration Sweat glands Microfluidics Skin phantom Perspiration Sweat Artificial skin In vitro testing Wearables Pell Perspiració Glàndules sudorípares Microfluídica A standardized and cost-effective perspiration phantom for in vitro testing is needed to replace the variable and resource consuming human tests at research level. Here, an alternative to the existing devices, which mainly are made of laser-perforated thin membranes, is presented using polydimethylsiloxane (PDMS) and soft lithography. The proposed method overcomes the fabrication challenges of replicating the eccrine sweat gland structure. Sweat glands conduits are faithfully defined in-plane and the skin interface is created by bonding multiple PDMS layers. Parameters such as sweat duct diameter, sweat gland density and wettability properties were successfully replicated Postprint (published version) 2020 Conference lecture Restricted access - publisher's policy