2026-04-17T02:53:41Zhttps://recercat.cat/oai/request

oai:recercat.cat:2117/3312292026-01-15T05:42:02Zcom_2072_1033col_2072_452950

Pigs are not susceptible to SARS‐CoV‐2 infection but are a model for viral immunogenicity studies Vergara-Alert, Júlia Rodon, Jordi Carrillo, Jorge Te, Nigeer Izquierdo‐Useros, Nuria Rodríguez de la Concepción, María Luisa Ávila‐Nieto, Carlos Guallar, Victor Valencia, Alfonso Cantero, Guillermo Blanco, Julià Clotet, Bonaventura Bensaid, Albert Segalés, Joaquim Àrees temàtiques de la UPC::Ciències de la salut COVID-19 (Disease) Inoculation Immunogenicity model Inoculation routes Lack of susceptibility Pig SARS-CoV-2 COVID-19 (Malaltia) Conventional piglets were inoculated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) through different routes, including intranasal, intratracheal, intramuscular and intravenous ones. Although piglets were not susceptible to SARS‐CoV‐2 and lacked lesions or viral RNA in tissues/swabs, seroconversion was observed in pigs inoculated parenterally (intramuscularly or intravenously). The CBIG Consortium (constituted by IRTA‐CReSA, BSC, & IrsiCaixa) is supported by Grifols pharmaceutical. The authors also acknowledge the crowdfunding initiative of https://www.yomecorono.com. Peer Reviewed Postprint (published version) 2020-10 Article https://onlinelibrary.wiley.com/doi/full/10.1111/tbed.13861 http://creativecommons.org/licenses/by-nc/3.0/es/ https://creativecommons.org/licenses/by-nc/4.0/ Open Access Attribution-NonCommercial 3.0 Spain Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Wiley