2026-04-05T12:37:45Zhttps://recercat.cat/oai/request
oai:recercat.cat:2117/281892026-02-04T03:24:09Zcom_2072_1033col_2072_452950
RECERCAT author Cárdenas Domínguez, Martha Ivón author Vellido Alcacena, Alfredo author Giraldo Arjonilla, Jesús 2014 This brief paper addresses the problem of visually assessing the natural discriminability of the different subtypes that characterize class C G-Protein-Coupled Receptors, which are membrane proteins of interest in pharmacology, from diverse transformations of their primary amino acid sequences. Visualization, achieved using nonlinear dimensionality reduction techniques, is used as an exploratory tool to increase the interpretability of the data subtype structure. Combined with a quantitative estimation of subtype overlapping, this approach should be of help to experts in proteomics.Peer ReviewedPostprint (published version) Restricted access - publisher's policy Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica Proteomics Bioinformatics Amino acids Biological membranes Molecular biology Proteins G protein coupled receptors Membrane proteins Nonlinear dimensionality reduction Nonlinear mappings Primary amino acid Primary sequences Quantitative estimation Visual interpretation Data visualization Proteòmica Bioinformàtica Visual interpretation of class C GPCR subtype overlapping from the nonlinear mapping of transformed primary sequences Conference report