2026-04-13T02:00:43Zhttps://recercat.cat/oai/requestoai:recercat.cat:2117/1218532026-02-07T06:51:21Zcom_2072_1033col_2072_452950
RECERCAT
author
Tinajero, Ernesto
author
Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon
author
Muñoz Guerra, Sebastián
author
de Paz, Maria Viola
author
Galbis Fuster, Elsa
2018-11-01
Metal-free catalysis was successfully applied to polymerize ¿-pentadecalactone (PDL) by ring-opening polymerization (ROP) using several amino-ended initiators, namely hexylamine, allylamine and O,O'-bis(3-aminopropyl)diethylene glycol. This polymerization method was suitable to prepare telechelic polyesters carrying functional-end groups. The technique was then extended to the synthesis of block copolymers by ROP of PDL using bisamino-ended poly(ethylene glycol) (Mn¿=¿2600) as macroinitiator. PPDLx-PEG56-PPDLx triblock copolymers with Mn ranging between ~4000 and ~90,000¿g¿·mol-1 were synthesized and extensively characterized by NMR, DSC, TGA and XRD. The amphiphilic copolymers thus produced were demonstrated to be able to self-assemble in nanoparticles with average diameters of ~100–200¿nm and morphologies highly depending on blocks lengths. The described synthetic route distinguishes in providing “clean” amphiphilic copolymers, which are attractive candidates for biomedical applications.Peer ReviewedPostprint (author's final draft)
http://creativecommons.org/licenses/by-nc-nd/3.0/es/ Open Access Attribution-NonCommercial-NoDerivs 3.0 Spain
Àrees temàtiques de la UPC::Enginyeria química
Nanocomposites (Materials)
Polyesters
Polymerization
Macrolactones polymerization
Amphiphilic block copolymers
Enzymatic ring-opening polymerization
Polyethyleneglycol-polyester copolymers
Amphiphilic block copolymer nanoparticles
Nanocompòsits (Materials)
Poliester
Polimerització
Metal-free catalyzed ring-opening polymerization and block copolymerization of ¿-pentadecalactone using amino-ended initiators
Article