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               <mods:name>
                  <mods:role>
                     <mods:roleTerm type="text">author</mods:roleTerm>
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                  <mods:namePart>Giner Tarrida, Lluís</mods:namePart>
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               <mods:name>
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                     <mods:roleTerm type="text">author</mods:roleTerm>
                  </mods:role>
                  <mods:namePart>Mercade, Montse</mods:namePart>
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               <mods:name>
                  <mods:role>
                     <mods:roleTerm type="text">author</mods:roleTerm>
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                  <mods:namePart>Torrent Camarero, Sergi</mods:namePart>
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               <mods:name>
                  <mods:role>
                     <mods:roleTerm type="text">author</mods:roleTerm>
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                  <mods:namePart>Punset Fuste, Miquel</mods:namePart>
               </mods:name>
               <mods:name>
                  <mods:role>
                     <mods:roleTerm type="text">author</mods:roleTerm>
                  </mods:role>
                  <mods:namePart>Pérez Antoñanzas, Román</mods:namePart>
               </mods:name>
               <mods:name>
                  <mods:role>
                     <mods:roleTerm type="text">author</mods:roleTerm>
                  </mods:role>
                  <mods:namePart>Delgado, Luis M.</mods:namePart>
               </mods:name>
               <mods:name>
                  <mods:role>
                     <mods:roleTerm type="text">author</mods:roleTerm>
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                  <mods:namePart>Gil Mur, Francisco Javier</mods:namePart>
               </mods:name>
               <mods:originInfo>
                  <mods:dateIssued encoding="iso8601">2018-04</mods:dateIssued>
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               <mods:abstract>Background: The topographical features on the surface of dental implants have been considered as a critical&#xd;
parameter for enhancing the osseointegration of implants. In this work, we proposed a surface obtained by a&#xd;
combination of shot blasting and double acid etching. The double acid etching was hypothesized to increase the&#xd;
submicron topography and hence further stimulate the biological properties of the titanium implant.&#xd;
Methods: The topographical features (surface roughness and real surface area), wettability and surface chemical&#xd;
composition were analyzed.&#xd;
Results: The results showed that the proposed method produced a dual roughness, mainly composed of randomly&#xd;
distributed peaks and valleys with a superimposed nanoroughness, and hence with an increased specific&#xd;
surface area. Despite the fact that the proposed method does not introduce significant chemical changes, this&#xd;
treatment combination slightly increased the amount of titanium available on the surface, reducing potential&#xd;
surface contaminants. Furthermore, the surface showed increased contact angle values demonstrating an enhanced&#xd;
hydrophobicity on the surface. The biological behavior of the implants was then assessed by culturing&#xd;
osteoblast-like cells on the surface, showing enhanced osteoblast adhesion, proliferation and differentiation on&#xd;
the novel surface.&#xd;
Conclusions: Based on these results, the described surface with dual roughness obtained by double acid etching&#xd;
may be a novel route to obtain key features on the surface to enhance the osseointegration of the implant. Our&#xd;
approach is a simple method to obtain a dual roughness that mimics the bone structure modified by osteoclasts&#xd;
and increases surface area, which enhances osseointegration of dental implants.Peer ReviewedPostprint (author's final draft)</mods:abstract>
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               <mods:accessCondition type="useAndReproduction">Open Access</mods:accessCondition>
               <mods:subject>
                  <mods:topic>Àrees temàtiques de la UPC::Enginyeria dels materials</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Osteoblasts</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Titanium</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Dental implants</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Acid etching</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Osteoblast differentiation</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Surface topography</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Titanium</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Wettability</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Titani</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Implants dentals</mods:topic>
               </mods:subject>
               <mods:titleInfo>
                  <mods:title>Double acid etching treatment of dental implants for enhanced biological properties</mods:title>
               </mods:titleInfo>
               <mods:genre>Article</mods:genre>
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