2026-04-13T01:39:14Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/5357692024-12-20T19:46:58Zcom_2072_300912com_2072_4427col_2072_301309

Trifluoromethylation of Carbonyl and Unactivated Olefin Derivatives by C(sp3)–C Bond Cleavage Cong, Fei Mega, Riccardo S. Chen, Jinhong Day, Craig S. Martin, Ruben Herein, we report a Cu-mediated trifluoromethylation of carbonyl-type compounds and unactivated olefins enabled by visible-light irradiation via σ C(sp3)−C bond-functionalization. The reaction is distinguished by its modularity, mild conditions and wide scope—even in the context of late-stage functionalization—thus offering a complementary approach en route to valuable C(sp3)−CF3 architectures from easily accessible precursors. 2022 2024-04-23T11:01:56Z 2022 2024-04-23T11:01:56Z 2022 2024-04-23T11:01:56Z 2022-11-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/2072/535769 https://doi.org/10.1002/anie.202214633 eng MICIU PID2021-123801NB-I00 European Research Council (ERC) under European Union's Horizon 2020 research and innovation program (grant agreement No 883756) China Scholarship Council (CSC) European Union's Horizon 2020 under the Marie Curie PREBIST grant agreement 754558. info:eu-repo/semantics/openAccess Creative Commons. Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) Wiley-VCH RECERCAT (Dipòsit de la Recerca de Catalunya)