2026-04-13T11:25:27Zhttps://recercat.cat/oai/request
oai:recercat.cat:2072/5329302024-12-20T22:50:15Zcom_2072_300912com_2072_4427col_2072_301309
RECERCAT author Li, Xuetong author Benet-Buchholz, Jordi author Escudero-Adán, Eduardo C. author Kleij, Arjan W. 2023-04-18T07:09:32Z2024-04-23T10:54:01Z 2024-01-13T01:45:05Z2024-04-23T10:54:01Z 2023-01-13 http://hdl.handle.net/2072/532930 https://doi.org/10.1002/anie.202217803 A conceptually novel catalytic domino approach is presented for the synthesis of highly functional 1,4-dihydro-2H-1,3-benzoxazine-2-one derivatives. Key to the chemoselectivity is a proper design of the precursor to override thermodynamically favored parasitic cyclization processes and empower the formation of the desired product through Thorpe-Ingold effects. The synthetic diversity of these CO2-based heterocycles is further demonstrated, and the isolation of a reaction intermediate supports an unusual ring-expansion sequence from an -alkylidene, five-membered cyclic carbonate to a six-membered cyclic carbamate by N-induced isomerization. eng Creative Commons Attribution-NonCommercial-NoDerivs License Silver-Mediated Cascade Synthesis of Functionalized 1,4-dihydro-2H-Benzo-1,3-Oxazin-2-Ones from Carbon Dioxide info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion URL https://recercat.cat/bitstream/2072/532930/1/ACIE%202023%2062%20e202217803_Silver-Mediated%20Cascade%20Synthesis.pdf File MD5 5199e64d44bbf0c00105d2cc0fa66027 1149940 application/pdf ACIE 2023 62 e202217803_Silver-Mediated Cascade Synthesis.pdf URL https://recercat.cat/bitstream/2072/532930/2/ACIE%202023%2062%20e202217803_Silver-Mediated%20Cascade%20Synthesis.pdf.txt File MD5 024cbf7c39e9284f023796fff0bc1928 29940 text/plain ACIE 2023 62 e202217803_Silver-Mediated Cascade Synthesis.pdf.txt