2026-04-14T00:52:45Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/5312932024-12-20T01:44:37Zcom_2072_199267com_2072_4427col_2072_201036

00925njm 22002777a 4500 dc Conde-Pueyo, N. author Guillamon, A. author Maull, V. author Pla, J. author Solé, R, author Sardanyés, J. author Vidiella, B. author 2021-11-29 Cognitive networks have evolved to cope with uncertain environments in order to make reliable decisions. Such decision making circuits need to respond to the external world in efficient and flexible ways, and one potentially general mechanism of achieving this is grounded in critical states. Mounting evidence has shown that brains operate close to such critical boundaries consistent with self-organized criticality (SOC). Is this also taking place in small-scale living systems, such as cells? Here, we explore a recent model of engineered gene networks that have been shown to exploit the feedback between order and control parameters (as defined by expression levels of two coupled genes) to achieve an SOC state. We suggest that such SOC motif could be exploited to generate adaptive behavioral patterns and might help design fast responses in synthetic cellular and multicellular organisms. © 2021 The authors. Published by IOP Publishing Ltd. http://hdl.handle.net/2072/531293 10.1088/2632-072X/ac35b3 Synthetic criticality in cellular brains