2026-04-17T01:57:54Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4890632026-01-12T09:47:39Zcom_2072_300912com_2072_4427col_2072_301309

Enzyme-like Hydrogen Atom Transfer (HAT) Based Endo-Functionalized Molecular Receptors Pan, Wenkai Grigoryeva, Anastasia Bacchiocchi, Corrado Ballester, Pablo Valgimigli, Luca Petroselli, Manuel We report a series of endo-functionalized molecular receptors based on a calix[4]pyrrole scaffold, which exhibit Hydrogen Atom Transfer (HAT) reactivity towards free-radicals (e.g., peroxyl radicals). The chemical structure and shape of the molecular receptors affect the affinity towards free-radicals, while host-guest interactions are used to fine-tune the HAT reactivity, mimicking enzyme modulation in biological systems. 2025-12-12 info:eu-repo/semantics/article http://hdl.handle.net/2072/489063 https://doi.org/10.1021/acs.orglett.5c04339 eng M.P. thanks Government of Catalunya for a Beatriu de Pinós 2021 grant (2021 BP 00028) Gobierno de España MICIU/AEI/10.13039/501100011033, FEDER/UE (PID2023-149233NB-IOO) and MICIU/AEI/10.13039/501100011033 (CEX2024-001469-S) CERCA Programme/Generalitat de Catalunya AGAUR (2021 SGR 00851) European Union - NextGenerationEU under the National Recovery and Resilience Plan (PNRR) - Mission 4 Education and research - Component 2 From research to business - Investment 1.1 Notice Prin 2022 - DD N. 104 del 2/2/2022, from PRIN20227XZKBY - Superoxide responsive redox-active systems and nano smart materials to target ferroptosis – FEROX - CUP J53D23008550006 W.P. acknowledges support from China Scholarship Council (CSC) http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/embargoedAccess Attribution 4.0 International ACS Publications RECERCAT (Dipòsit de la Recerca de Catalunya)