2026-04-14T09:35:36Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4832122025-04-03T12:15:12Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc Gil, Patricia author Exbrayat, Antoni author Loire, Etienne author Rakotoarivony, Ignace author Charriat, Florian author Morel, Côme author Baldet, Thierry author Boisseau, Michel author Marie, Albane author Frances, Benoît author L'Ambert, Gregory author Bessat, Mohamed author Otify, Yehia author Goffredo, Maria author Mancini, Giuseppe author Busquets, Núria author Birnberg, Lotty author Talavera Forcades, Sandra author Aranda Pallero, Carles author Ayari, Emna author Mejri, Selma author Sghaier, Soufien author Bennouna, Amal author El Rhaffouli, Hicham author Balenghien, Thomas author Chlyeh, Ghita author Fassi Fihri, Ouafaa author Reveillaud, Julie author Simonin, Yannick author Eloit, Marc author Gutierrez, Serafin author 2023 Our knowledge of the diversity of eukaryotic viruses has recently undergone a massive expansion. This diversity could influence host physiology through yet unknown phenomena of potential interest to the fields of health and food production. However, the assembly processes of this diversity remain elusive in the eukaryotic viromes of terrestrial animals. This situation hinders hypothesis-driven tests of virome influence on host physiology. Here, we compare taxonomic diversity between different spatial scales in the eukaryotic virome of the mosquito Culex pipiens. This mosquito is a vector of human pathogens worldwide. The experimental design involved sampling in five countries in Africa and Europe around the Mediterranean Sea and large mosquito numbers to ensure a thorough exploration of virus diversity. A group of viruses was found in all countries. This core group represented a relatively large and diverse fraction of the virome. However, certain core viruses were not shared by all host individuals in a given country, and their infection rates fluctuated between countries and years. Moreover, the distribution of coinfections in individual mosquitoes suggested random co-occurrence of those core viruses. Our results also suggested differences in viromes depending on geography, with viromes tending to cluster depending on the continent. Thus, our results unveil that the overlap in taxonomic diversity can decrease with spatial scale in the eukaryotic virome of C. pipiens. Furthermore, our results show that integrating contrasted spatial scales allows us to identify assembly patterns in the mosquito virome. Such patterns can guide future studies of virome influence on mosquito physiology. http://hdl.handle.net/2072/483212 Virome Mosquito Culex pipiens Metagenomics Spatial scale influences the distribution of viral diversity in the eukaryotic virome of the mosquito Culex pipiens