2026-04-13T13:37:54Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4781092024-11-04T08:40:13Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc Manso, Luis author Ramchandani-Vaswani, Avinash author Romero, Ignacio author Sánchez-Lorenzo, Luisa author Bermejo-Pérez, Maria José author Estévez-García, Purificación author Fariña-Madrid, Lorena author García García, Yolanda author Gil-Martin, Marta author Quindós, María author Universitat Autònoma de Barcelona author 2024 Cervical cancer (CC) is the fourth most common cancer and the fourth leading cause of mortality in women worldwide. It is strongly associated with high-risk human papillomavirus infection. High-income countries that have implemented human papillomavirus (HPV) vaccination and screening programs have seen dramatic reductions in CC incidence, while developing countries where these programs are not available continue to experience high rates of CC deaths. In early-stage CC, the primary treatment is surgery or radiotherapy, whereas concurrent chemo-radiotherapy (CRT) remains the conventional approach in locally advanced stages until the upcoming approval of immunotherapy. The incorporation of immunotherapy in combination with chemotherapy (with or without bevacizumab) in first line and as monotherapy in second line after platinum-based chemotherapy, has significantly increased overall survival (OS) in recurrent or metastatic CC. The purpose of this guideline is to summarize the most relevant evidence in the diagnosis, treatment, and follow-up of CC and to provide evidence-based recommendations for clinical practice. http://hdl.handle.net/2072/478109 Cervical cancer Guideline Diagnosis Treatment SEOM-GEICO Clinical Guidelines on cervical cancer (2023)