2026-04-17T00:51:44Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4759962025-08-31T17:13:06Zcom_2072_98col_2072_378192

Post COVID-19 Condition in Children and Adolescents : An Emerging Problem Izquierdo-Pujol, Jon Moron-Lopez, Sara Dalmau, Judith Gonzalez-Aumatell, Alba Carreras-Abad, Clara Méndez Hernández, Maria Rodrigo Gonzalo de Líria, Carlos Martínez Picado, Francisco Javier Universitat Autònoma de Barcelona Adolescents Children COVID-19 Long-covid-19 Long-haul COVID Post COVID-19 condition Post-acute COVID-19 syndrome The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection became a pandemic in 2020 and by March 2022 had caused more than 479 million infections and 6 million deaths worldwide. Several acute and long-term symptoms have been reported in infected adults, but it remains unclear whether children/adolescents also experience persistent sequelae. Hence, we conducted a review of symptoms and pathophysiology associated with post-coronavirus disease 2019 (post-COVID-19) condition in children and adolescents. We reviewed the scientific literature for reports on persistent COVID-19 symptoms after SARS-CoV-2 infection in both children/adolescents and adults from 1 January 2020 to 31 March 2022 (based on their originality and relevance to the broad scope of this review, 26 reports were included, 8 focused on adults and 18 on children/adolescents). Persistent sequelae of COVID-19 are less common in children/adolescents than in adults, possibly owing to a lower frequency of SARS-CoV-2 infection and to the lower impact of the infection itself in this age group. However, cumulative evidence has shown prolonged COVID-19 to be a clinical entity, with few pathophysiological associations at present. The most common post-COVID-19 symptoms in children/adolescents are fatigue, lack of concentration, and muscle pain. In addition, we found evidence of pathophysiology associated with fatigue and/or headache, persistent loss of smell and cough, and neurological and/or cardiovascular symptoms. This review highlights the importance of unraveling why SARS-CoV-2 infection may cause post-COVID-19 condition and how persistent symptoms might affect the physical, social, and psychological well-being of young people in the future. 2022 Article Agencia Estatal de Investigación PID2019-109870RB-I00 Frontiers in Pediatrics ; Vol. 10 (may 2022) open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/