2026-04-14T03:20:45Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4752232025-08-31T17:08:10Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc Nomah, Daniel Kwakye author Reyes-Urueña, Juliana author Alonso, Lucía author Díaz, Yesika author Moreno-Fornés, Sergio author Aceitón, Jordi author Bruguera Riera, Andreu author Martín-Iguacel, Raquel author Imaz, Arkaitz author Gutierrez, Mª del Mar author Román, Ramón W. author Suanzes, Paula author Ambrosioni, Juan author Casabona-Barbarà, Jordi author Miró, José M author Llibre, Josep M. author Universitat Autònoma de Barcelona author 2023 People with HIV (PWH) may be more susceptible to SARS-CoV-2 infection and worse clinical outcomes. We investigated the disparity in SARS-CoV-2 vaccination coverage between PWH and those without HIV (PWoH) in Catalonia, Spain, assessing primary and monovalent booster vaccination coverage from December 2021 to July 2022. The vaccines administered were BNT162, ChAdOx1-S, mRNA-127, and Ad26.COV2.S. Using a 1:10 ratio of PWH to PWoH based on sex, age, and socioeconomic deprivation, the analysis included 201,630 individuals (183,300 PWoH and 18,330 PWH). Despite a higher prevalence of comorbidities, PWH exhibited lower rates of complete primary vaccination (78.2% vs. 81.8%, p < 0.001) but surpassed PWoH in booster coverage (68.5% vs. 63.1%, p < 0.001). Notably, complete vaccination rates were lower among PWH with CD4 <200 cells/μL, detectable HIV viremia, and migrants compared to PWoH (p < 0.001, all). However, PWH with CD4 < 200 cells/μL received more boosters (p < 0.001). In multivariable logistic regression analysis of the overall population, a prior SARS-CoV-2 diagnosis, HIV status, migrants, and mild-to-severe socioeconomic deprivation were associated with lower primary vaccination coverage, reflecting barriers to healthcare and vaccine access. However, booster vaccination was higher among PWH. Targeted interventions are needed to improve vaccine coverage and address hesitancy in vulnerable populations. Booster doses COVID-19 HIV SARS-CoV-2 Vaccination Comparative Analysis of Primary and Monovalent Booster SARS-CoV-2 Vaccination Coverage in Adults with and without HIV in Catalonia, Spain